Journal article
Impact of Maternal Obesity on Inhaled Corticosteroid Use in Childhood: A Registry Based Analysis of First Born Children and a Sibling Pair Analysis
AJ Lowe, C Ekeus, L Bråbäck, K Rajaleid, B Forsberg, A Hjern
Plos One | PUBLIC LIBRARY SCIENCE | Published : 2013
Abstract
Background:It has been proposed that maternal obesity during pregnancy may increase the risk that the child develops allergic disease and asthma, although the mechanisms underpinning this relationship are currently unclear. We sought to assess if this association may be due to confounding by genetic or environmental risk factors that are common to maternal obesity and childhood asthma, using a sibling pair analysis.Methods:The study population comprised a Swedish national cohort of term children born between 1992 and 2008 to native Swedish parents. Maternal body mass index (BMI) was measured at 8-10 weeks gestation. Unconditional logistic regression models were used to determine if maternal ..
View full abstractGrants
Awarded by Swedish Research Council through the Swedish Initiative for Research on Microdata in the Social And Medical Sciences (SIMSAM) network
Funding Acknowledgements
This project was supported by Swedish Research Council through the Swedish Initiative for Research on Microdata in the Social And Medical Sciences (SIMSAM) network, grant no. 2008-7491, who provided financial support to A.L. and L.B. to undertake this project. Also, A.L. was supported by the Australian National Health and Medical Research Council, C.E. was supported with grants from the Swedish Research Council. The funders had no role in study design, data collection and analysis, decision to publish, or preparation of the manuscript.